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caki2 cell lines  (ATCC)


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    ATCC caki2 cell lines
    Biological functions of ferroptosis-related genes in ccRCC cells. (A) CCK-8 kit assay showed that OSRC2 and <t>CAKI2</t> cells viability increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (B) Wound healing assay experiments showed that knocking down EPAS1 and ALDH3A2 led to increase of invasive OSRC2 and CAKI2 cells, while decreased after silencing BID, AURKA and PLA2G6. (C) Plate colony formation assay showed that colony formation of OSRC2 and CAKI2 cells increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (Scalebar-100 μm *p < 0.05, **p < 0.01, and ***p < 0.001, n.s no significance, according to Student’s t-test).
    Caki2 Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 654 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/caki2 cell lines/product/ATCC
    Average 97 stars, based on 654 article reviews
    caki2 cell lines - by Bioz Stars, 2026-02
    97/100 stars

    Images

    1) Product Images from "The biological function and prognostic significance of ferroptosis-related genes in clear cell renal cell carcinoma"

    Article Title: The biological function and prognostic significance of ferroptosis-related genes in clear cell renal cell carcinoma

    Journal: Frontiers in Pharmacology

    doi: 10.3389/fphar.2025.1515552

    Biological functions of ferroptosis-related genes in ccRCC cells. (A) CCK-8 kit assay showed that OSRC2 and CAKI2 cells viability increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (B) Wound healing assay experiments showed that knocking down EPAS1 and ALDH3A2 led to increase of invasive OSRC2 and CAKI2 cells, while decreased after silencing BID, AURKA and PLA2G6. (C) Plate colony formation assay showed that colony formation of OSRC2 and CAKI2 cells increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (Scalebar-100 μm *p < 0.05, **p < 0.01, and ***p < 0.001, n.s no significance, according to Student’s t-test).
    Figure Legend Snippet: Biological functions of ferroptosis-related genes in ccRCC cells. (A) CCK-8 kit assay showed that OSRC2 and CAKI2 cells viability increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (B) Wound healing assay experiments showed that knocking down EPAS1 and ALDH3A2 led to increase of invasive OSRC2 and CAKI2 cells, while decreased after silencing BID, AURKA and PLA2G6. (C) Plate colony formation assay showed that colony formation of OSRC2 and CAKI2 cells increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (Scalebar-100 μm *p < 0.05, **p < 0.01, and ***p < 0.001, n.s no significance, according to Student’s t-test).

    Techniques Used: CCK-8 Assay, Wound Healing Assay, Colony Assay



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    Image Search Results


    Biological functions of ferroptosis-related genes in ccRCC cells. (A) CCK-8 kit assay showed that OSRC2 and CAKI2 cells viability increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (B) Wound healing assay experiments showed that knocking down EPAS1 and ALDH3A2 led to increase of invasive OSRC2 and CAKI2 cells, while decreased after silencing BID, AURKA and PLA2G6. (C) Plate colony formation assay showed that colony formation of OSRC2 and CAKI2 cells increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (Scalebar-100 μm *p < 0.05, **p < 0.01, and ***p < 0.001, n.s no significance, according to Student’s t-test).

    Journal: Frontiers in Pharmacology

    Article Title: The biological function and prognostic significance of ferroptosis-related genes in clear cell renal cell carcinoma

    doi: 10.3389/fphar.2025.1515552

    Figure Lengend Snippet: Biological functions of ferroptosis-related genes in ccRCC cells. (A) CCK-8 kit assay showed that OSRC2 and CAKI2 cells viability increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (B) Wound healing assay experiments showed that knocking down EPAS1 and ALDH3A2 led to increase of invasive OSRC2 and CAKI2 cells, while decreased after silencing BID, AURKA and PLA2G6. (C) Plate colony formation assay showed that colony formation of OSRC2 and CAKI2 cells increased after silencing EPAS1 and ALDH3A2, while decreased after silencing BID, AURKA and PLA2G6. (Scalebar-100 μm *p < 0.05, **p < 0.01, and ***p < 0.001, n.s no significance, according to Student’s t-test).

    Article Snippet: The OSRC2 and CAKI2 cell lines, commonly employed in renal cancer research ( ; ; ; ), were obtained from the American Type Culture Collection (ATCC).

    Techniques: CCK-8 Assay, Wound Healing Assay, Colony Assay

    Average B score summary of gene hits Summary of the 31 gene hits identified to significantly decrease tumor cell proliferation. Clone references for the specific lentiviral constructs used to generate growth effects are shown. Average B-scores (n=3) for all four cell lines tested are provided.

    Journal: Oncotarget

    Article Title: Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration

    doi:

    Figure Lengend Snippet: Average B score summary of gene hits Summary of the 31 gene hits identified to significantly decrease tumor cell proliferation. Clone references for the specific lentiviral constructs used to generate growth effects are shown. Average B-scores (n=3) for all four cell lines tested are provided.

    Article Snippet: ACHN, A498, Caki1, and Caki2 ccRCC cell lines were purchased from American Type Culture Collection (Manassas, VA).

    Techniques: Construct, Binding Assay, Derivative Assay